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Monika Konaklieva

Associate Professor
Department of Chemistry

  • Dr. Konaklieva’s research is in the area of exploring different approaches for delaying of microbial resistance. Current projects include computer-aided design and synthesis of novel beta-lactams as well as development of synthetic methodology for preparation of
    other “non-conventional” candidates as beta-lactamase and Human Leukocyte Elastase inhibitors.
  • Degrees

    PhD, Organic Chemistry, State University of New York at Buffalo
    MS, Chemistry, Institute of Organic Chemistry, Sofia, Bulgaria
    MS, Pharmacy, State University Medical Academy, Sofia, Bulgaria

  • CAS - Chemistry
  • Beeghly - 306

  • (202) 885-1777 (Office)
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    at 202-885-5950 or submit a request.


Scholarly, Creative & Professional Activities

Honors, Awards, and Fellowships

  • NIST-Sponsored Undergraduate Student Summer Fellowship (2003)
  • NIST-Sponsored Undergraduate Student Summer Fellowship (2002)
  • The Research Corporation, Beta-Lactamase activated NO-containing beta-lactams (2002)

Selected Publications

  • Monika I. Konaklieva and Balbina J. Plotkin, “Bioisosters of Beta-Lactams as Anti-Infectives" Current Medicinal Chemistry Anti-Infective Agents, 2,4 (2003)
  • Timothy E. Long; Edward Turos; Monika I. Konaklieva; Allison L. Blum; Amal Amry;Ejae A. Baker; Lita S. Suwandi; Melodie D. McCain; Miti F. Rahman; Sonja Dickey;Daniel V. Lim, “Effect of Aryl Ring Fluorination on the Antibacterial Properties of C4 Aryl- Substituted N-Methylthio beta- Lactams” Bioorganic & Medicinal Chemistry, 11,1859, (2003)
  • Jeffrey R. Deschamps., Lita Suwandi, and Monika Konaklieva, “3,3-Bis(methylthio)-2-oxo-N-phenylpropanamide”Acta Crystallographica Section E, Structure Reports, E59, 1,(2003)

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